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![]() MJP Rohilkhand University M.Sc. Plant Science Syllabus PLANT SCIENCE SYLLABUS PAPER I: GENETICS & CYTOGENETICS UNIT I A. Linkage and Crossing over : Concept of linkage and factors affecting true strength of Linkage. B. Theories of crossing over at chromosomal & molecular level (Chiasmata, Precocity, Bellings, Whitehouse and Holiday model, Sobel’s concept. C. Measurement of linkage from F2 and back cross data, Genetic map of chromosomes, double crossing over, interference and coincidence. UNIT II A. Mutation : Types of mutation, mutation rate, Base substitution (transition and transversion) Frame shift mutation. Mechanism of gene mutation. B. Induction of mutation : Target theory, Peroxide formation, UV rays and Thymine dimer, Incorporation of base analogue. Tautomerization and chemical alteration in nucleic acids. C. Detection of mutation in plants and Drosophila. UNIT III A. Sex determination : Theories of sex determination in Drosophila, plant & man, Single gene harmonal control of sex and sex reversal and gynandromorph. B. Human genetic disorder : Sex linked inheritance, (Colour blindness, haemophilia, Hypertichosis). Physiological disorders : Phenylketoneurea, Alkaptonurea, Albinism and sickle cell anaemia and Syndromes : Down, Klinfelter and Turnor C. Extrachromosomal Inheritance : Cytoplasmic inheritance in Mirabilis, Maize and Paramecium. Delayed inheritance, Dauer modification. UNIT IV A. Polyploidy : Classification, cytological and genetical method of identification of autopolyploids and allopolyploids. B. Classification, method of production, identification and meiotic behaviour of aneuploids (Monosomics, Nullisomics and trisomics). C. Structural alteration in chromosome : Deletion, Duplication, Inversion & Translocation, hetrozygote. UNIT V A. Concept of Gene, Genetic load & Genetic councelling. B. Nuclear DNA content, C-Value paradox, Cot value and its significance C. in situ hybridization - concept & Techniques, flow cytometry in karyo type analysis. ![]() ![]() ![]() ![]() |
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