Jayanta Mukhopadhyay Bose Institute

Can you please provide me the details of the Jayanta Mukhopadhyay at the Bose Institute?

As you are looking to get the details of the professor Jayanta Mukhopadhyay of the Bose Institute so here is some information about him that can help you-

Jayanta Mukhopadhyay
Assistant Professor,
Department of Chemistry

Ph.D (Biochemistry & Biophysics),
Jadavpur University, 2000

Research interest of the professor of the institute

Transcription is the first step in gene expression where most regulation occurs. RNAP core enzyme together with sigma factor(s) and/or numerous regulator(s) orchestrates the gene expression in bacteria.

The lab of the institute seeks to characterize the interactions among RNAP, sigma factors, and regulators required for various gene expressions in Mycobacterium tuberculosis. The proposed work of the professor will use integrated biophysical, biochemical and genetic approaches, along with a recombinant in vitro transcription system to address two specific aims:

1. Determine the role of alternative sigma factors in gene regulation of M. tuberculosis

2. Identify and characterize inhibitors of M. tuberculosis gene expression.

Relevant publications by the professor at the institute

Mukhopadhyay J, Das K, Ismail S, Koppstein D, Jang M, Sarafianos St, Tuske S, Hudson B, Patel J, Jansen R, Höfle G, Arnold E, and Ebright RH (2008). The RNA polymerase "switch region" is a target for inhibitors. Cell, 135: 295-305.

Pavlova O, Mukhopadhyay J, Sineva E, Ebright RH, Severinov K. (2008) Structure-activity analysis of Microcin J25. J Biol Chem., 283: 25589- 95.

Mukhopadhyay J, Sineva E, Knight J, Levy RL, and Ebright RH (2004) Antibacterial peptide microcin J25 (MccJ25) inhibits transcription by binding within, and obstructing, the RNA polymerase secondary channel. Mol Cell, 14, 739-751.

Mukhopadhyay J, Mekler V, Kortkhonjia E, Kapanidis AN, Ebright YW, Ebright RH (2003) Fluorescence resonance energy transfer (FRET) in analysis of transcription-complex structure and function. Methods Enzymol, 371, 144-159.

To get more details of the professor please contact the institute at the following address.

Address-

Bose Institute
P 1/12, CIT Rd, Kankurgachi, Kolkata, West Bengal 700054 ‎
033 2355 9544

Map-

__________________
Answered By StudyChaCha Member