CIMAP PhD

When will Central Institute of Medicinal and Aromatic Plants (CIMAP) invite application for admission in CIMAP Ph.D program in 2012? What is minimum qualification required for get admission in CIMAP Ph.D program in 2012?

Central Institute of Medicinal and Aromatic Plants is inviting application for the PhD program.

Here I am providing you syllabus for the PhD program.

100 level courses
Course Number Course Content
BIO-CIMAP-1-001 Biostatistics

Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses:
(a) parametric tests: t-test, z-test, chi-squares test, ANOVA
(b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CIMAP-1-002 Computation/bioinformatics

Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses.
Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications
Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet
Introduction to Word, Powerpoint and Excel
Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics.
Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems.
Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.


BIO-CIMAP-1-003 Basic Chemistry

Thermodynamics
Solutions and Ions
Chemical bonding and molecular structure
Chemical Kinetics
Stereochemistry
Introduction to drug discovery (Medicinal chemistry approach)
Drug target, discovery and development (forward and reverse approach
BIO-CIMAP-1-004 Research Methodology, Communication/ethics/safety

Philosophy and structure of scientific thoughts, Objective and Motivation of Research, Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure
Research methodology, communication, ethics, safety
Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it
Study design: Recognizing and minimizing bias
Experiment design: Sometimes less is more and the importance of controls
Good lab practices: Record keeping, organizing data, organizing the lab space
Data interpretation; objectivity, quantification, double blind studies and necessity of statistics
Comunicating your data:writing up your research
Comunicating your data: presenting your findings
Radiation safety
Chemical and Biosafety
Intellectual property rights
What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation
200 level courses
Course number Course content
BIO-CIMAP-2-001 Biotechniques and Instrumentation (compulsory)

Chromatography, Mass spectrometry and Protein identification, Protein interactions : Isothermal calorimetry, Analytical ultracentrifuge, Surface Plasmon resonance, Fluorescence spectroscopy, FACS, Imaging: Electron microscopy, Confocal microscopy, Atomic force microscopy, Single molecule imaging and structure determination of protein complexes, In vivo imaging, RNA/ DNA quantitation (capillary based methods), DNA and protein microarray, NMR, X-Ray crystallography
BIO-CIMAP-2-002 Biology of Macromolecules

Basic concept: life forms from prokaryotes to eukaryotes; molecules, building blocks;Water and Buffer systems; Nucleic acids and proteins; Lipids; Sugars; Anabolism and catabolism of building blocks and macromolecules
BIO-CIMAP-2-003 Biology of Inheritance

Evolution, Mendel's Laws of Inheritance, Chromosome theory of inheritance, Co-dominance and incomplete dominance; pleiotropism, genotypic interactions, epistasis, mechanism of epistasis; Mitosis and Meiosis in plants, animal and human. Cell cycle and cell division. Linkage and mapping in eukaryotes; FISH / GISH, coincidence and interference. Concept of sex determination and patterns in plants and animals; sex chromosomes; Sex-linked, sex-limited and sex-influenced characters. Extra-nuclear inheritance: determining non-Mendelian Inheritance; maternal effects, cytoplasmic inheritance. Nature and components of variation, heritability and genetic advance, self incompatibility and male sterility system, role of mutations and chromosome modifications, induction of polyploidy and its significance, Genetic consequences of self and cross fertilization, mating systems, apomixes.
BIO-CIMAP-2-004 Biology of Infection

Introduction to microorganisms, types of infection, development and manifestation, defence against infection, prevention of infections, resistance in infectious organisms.
BIO-CIMAP-2-005 Genomics: Information flow in Biological Systems

Introduction to genomics; Cloning vectors (plasmids, cosmids, BAC, PAC, YAC) genomes and genes; genome organization; Techniques in genomics; Advance sequencing techniques and their application in genomics; DNA Sequence assembly; Application of genomics tools in genotype designing and drug discovery; Defining the genome: from size to functions; Chloroplast and mitochondrial genomes; Functional genomics and beyond.
BIO-CIMAP-2-006 Protein Science and Proteomics

Introduction proteomics; Extraction of proteins; Separation of proteins; Organelle proteomics; Protein identification and characterization; Structural proteomics and computational analysis; Protein-protein interactions; Techniques for Proteome research; High throughput proteomic screening for novel bioactive peptides/proteins/enzymes
BIO-CIMAP-2-007 Systems Biology

Central dogma of life, Concept of genome, transcriptome, proteome and metabolome; Comparasion of genomes/transcriptome/proteomes /metabolomes; Synteny; Geneexpression subsets; Primary and secondary metabolism; Analytical tools for systems biology; Applications in plant research.
BIO-CIMAP-2-008 Xenobiotic Interaction and Response

Toxicokinetics, general toxicology, phytotoxicology, environmental toxicology, adverse drug reaction, drug safety profiling and regulatory toxicology.
BIO-CIMAP-2-009 Plant-Microbe Interaction

Plant growth promoting microbes; Microbial bio-inoculants; Nitrogen fixing microorganisms: mechanism of nitrogen fixation; Plant diseases and management, Biological control of pathogens; Role of microbial technology in agriculture.
BIO-CIMAP-2-010 Plant Environment Interaction

Introduction to environment: classification, components of environment; Ecology and ecosystems; Symbiotic relationships; Plant responses to abiotic & biotic stresses; Plant- soil interactions.
BIO-CIMAP-2-011 Molecular Therapeutics

General pharmacology, phytopharmacology, drug receptor interactions, in-vitro and in-vivo bioassays in drug discovery and development
BIO-CIMAP-2-015 Crop Protection

Major pests of crops; Insect - plant relationship; Principles of insect physiology; Toxicology and pathology; Insecticide resistance and residue monitoring; Biopesticides and integrated pest management.
BIO-CIMAP-2-016 Developmental Biology-Plants

Development and differentiation in plants: Physiological and biochemical basis; Genetic regulation of spatial and temporal development; Genetic regulation of plant growth and development, gametophyte development, fertilization and seed development, seed germination, seed adaptation in relation to environment; Effect of development on plant secondary metabolism.
BIO-CIMAP-2-017 Epigenetics and Chromatin Organization

Introduction to epigenetics; Techniques in epigenetics; Epigenetics in plants evolution, adaptation and environmental stress, Chromatin structure; Organization of nucleosome and chromosomes; Molecular aspects of cell division and cell cycle. DNA replication in Prokaryotes and Eukaryotes. RNA transcription and processing; Transcriptional regulation in prokaryotes and eukaryotes; Protein synthesis, protein modifications and secretion; Regulation of protein synthesis; Transposable genetic elements, Types and mechanisms of transposition.
BIO-CIMAP-2-021 Molecular Breeding of Plants

Introduction and techniques in molecular breeding; Morphological and Molecular markers, QTL analysis; Application of molecular breeding in plants; Development of mapping populations; Molecular mapping and gene tagging of important traits; Marker-assisted selection; Gene pyramiding.
BIO-CIMAP-2-024 Bioresources and Bioprospection
Phyto-taxonomy principles and fundamentals; Biodiversity: principles, importance and characterization; Threats, conservation and gene banking; Remote sensing and GIS concepts and approaches; Bio prospection: principle, techniques and applications.
BIO-CIMAP-2-206 Crop Production Systems

Sustainable agriculture: crop growth and yield, adaptation of plants to water variation; Soil fertility and nutrient management; IPNMS system; Precision agriculture; Agroforestry systems; Soil-plant-water relationship; Energy concepts; Physio-morphological behaviour of plants; Isotopes and radiation techniques; Metabolic and hormonal responses; Natural resource management.
BIO-CIMAP-2-207 Intellectual Property Management

BIO-CIMAP-2-208 Applied and fundamental aspects of In Vitro Plant/Cell/Tissue/ Organ Culture

Introduction to Plant Cellular totipotency: Process and mechanism; Differentiation, morphogenesis and Somatic embryogenesis; Haploids: Androgenic and gynogenic; Endosperm culture, triploid production and its applications; Somaclonal variations; Somatic hybridization; In vitro production of commercially useful secondary metabolites; Scale up studies using bioreactors; Biotransformations.
BIO-CIMAP-2-209 Crop Modelling and System Research

Systems-definition, input-output relationships, crop modelling-static descriptive and explanatory models, modelling techniques, Crop modelling- methods for water and nutrient stress effects, data requirement and limitations, Modelling crop-environment interaction, applications of simulation modelling in environmental impact assessment; Agro and post-harvest technology development and dissemination.
300 level courses
Course number Course content
BIO-CIMAP-3-001 Seminar Course (compulsory)
BIO-CIMAP-3-003 Cell and Tissue Engineering

Transgenic plants: Advances in producing transgenics, selection, identification, molecular analysis for confirmation and applications. Molecular farming: salient achievements and future prospects. Metabolic engineering for pathway modulations: propose and potentials. Agrobacterium as natural genetic engineer; molecular mechanism, controlling factors and advantages.
BIO-CIMAP-3-004 Frontiers of Biology: Synthetic Biology

Molecular biology of metabolic processes in plants and microbes. Molecular regulators of metabolic pathways. Approaches of engineering metabolic pathways in heterologous systems (plants, microbes and insect cell lines)
BIO-CIMAP-3-005 Advanced Bioinformatics

Databases and resources in Bioinformatics, Gene expression analysis, Sequence analysis and algorithms, Protein and nucleic acid properties, Taxonomy and phylogeny, Next generation sequencing, Structural Bioinformatics, Molecular modeling and simulations, Comparative and functional genomics, Modelling biological systems, Drug design, Advanced programming and scripting.
BIO-CIMAP-3-009 Gene Environment Interaction

Recent advances in plant responses to biotic and abiotic stresses. Impact of environmental changes at molecular and cellular levels in plants.
BIO-CIMAP-3-010 Advances in Gene Silencing

Gene silencing: Mechanism, techniques and applications; Antisense RNA technology, RNAi and VIGS; siRNA & miRNA : Biogenesis, translocations, Methods of isolation, characterization and application.
BIO-CIMAP-3-013 Advances in Crop Disease Management

Genetic improvement of microbial bio control agents-metabolites, rhizosphere colonization, disease control; Mass multiplication of bio control agents, delivery systems, monitoring, commercial bio pesticides, quality control of bio control agents; Enzyme based formulations-status and problems; Molecular diagnostic methods, pathogen-derived resistance, genetic engineering approaches to develop disease resistant plants; Integrated disease management strategies.
BIO-CIMAP-3-014 Integrated Pest Management

Trends in the development of Integrated Pest Management in national and international level, IPM Theory and Practice, economic threshold concept and economic consideration, Biological control agents, Integration of different methods of pest management, Cost-benefit ratios, case studies of successful IPM programmes
BIO-CIMAP-3-206 Anti microbial agents and drug resistance

Classification of antimicrobial agents; mechanism of antimicrobial agents, mechanism of drug resistance, strategies for combating drug resistance
BIO-CIMAP-3-207 Drug delivery and Pharmaceutical formulations

Introduction to pharmaceutical dosage forms, Conventional methods for drug delivery, Novel Drug Delivery Systems (NDDS)
BIO-CIMAP-3-208 In-vitro secondary metabolite production and biotransformation

Production of commercially useful secondary metabolites by callus/ cell suspension/ hairy root cultures: induction, kinetics of growth and product formation, optimization of physical/chemical factors, precursor-feeding, permeabilization, elicitation and immobilization for improved product recovery. Scale up studies using bioreactors for commercial production-general principles of bioreactors, design optimizations and downstream processing. Biotransformations using cell/hairy root cultures for generating pharmaceutical lead molecules.
BIO-CIMAP-3-209 Plant Pathogenesis

Principles and concepts in host-pathogen relationship, recognition concept and infection for pathogens; role of enzymes, toxins, growth regulators in disease development; oxidative burst; phytoalexins, PR proteins, elicitors-defense strategies, signal transduction, systemic acquired resistance and induced systemic resistance, defense genes, hypersensitive reaction, programmed cell death, viral induced gene silencing, R-gene expression and transcription profiling
BIO-CIMAP-3-210 Biology & Chemistry of Natural Products

Classification of plant metabolites – primary & secondary metabolites; various classes of secondary metabolites – Alkaloids, Terpenoids, Phenylpropanoids and their complexes; extraction procedures for natural products; structure elucidation methods for identification of new compound/NCEs; structural modification of natural products. Bioprospecting natural products.
BIO-CIMAP-3-211 Biology of inflammation and diseases

Activated innate and adapted immune responses, Pathobiology of inflammation, inflammatory reactions in infectious and non-infectious disease conditions, auto-immune disorders
BIO-CIMAP-3-212 Soil and crop management

Chemistry of soil fertility, principles and methods of soil and plant analysis, fertilizer and fertilizers use technology, mineral nutrition of plants, manures and fertilizers, development and management and of salt affected and other problematic soils, agrometrology, cropping and farming systems, allelochemicals interaction in plants and soils.

The Admission to the CIMAP is through the Entrance and through interview.
The PHD program is conducted through the JNU university.
The interview Schedule for 2012 was 15 December 2011 at Central Institute of Medicinal and Aromatic Plants, Lucknow.
Here I am attaching the pdf file for the more details for the PHD program.

Attached Files Available for Download

CIMAP-JNU Ph.D PROGRAMME 2012.pdf (681.3 KB, 29 views)

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Give me syllabus for PhD in Central Institute of Medicinal and Aromatic Plants