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Default Sathyabama Institute of Science and Technology B.Sc - Biotechnology SBB 1201 Immunology Syllabus

Sathyabama Institute of Science and Technology B.Sc - Biotechnology SBB 1201 Immunology Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO & CHEMICAL ENGINEERING

SBB1201 IMMUNOLOGY
L T P Credits Total Marks
4 0 0 4 100

UNIT 1 IMMUNOLOGY AND IMMUNITY 12 Hrs.
History of Immunology – Host-parasite relationship – Immunity – Innate and acquired immunity – Humoral and Cellmediated
immunity.

UNIT 2 IMMUNE CELLS 12 Hrs.
Structure, Functions and Properties of: Immune Cells – Stem cell, T cell, B cell, NK cell, Macrophage, Neutrophil,
Eosinophil, Basophil, Mast cell, Dendritic cell; and Immune Organs – Bone Marrow, Thymus, Lymph Node, Spleen,
GALT, MALT, CALT

UNIT 3 ANTIGENS 12 Hrs.
Antigens – Types, properties – Immunoglobulins – Structure, types and properties – Complement – Classical and
alternative pathways.

UNIT 4 ANTIBODIES 12 Hrs.
Structure, Types, Functions and Properties of antibodies; Antigenic determinants on antibodies (Isotypic, allotypic,
idiotypic); VDJ rearrangements; Monoclonal and Chimeric antibodies. Antibody reactions – Agglutination – Precipitation
–Complement fixation – Immunofluorescence – ELISA-RIA.

UNIT 5 IMMUNOLOGICAL REACTIONS 12 Hrs.
Hypersensitivity reactions – Antibody mediated – Type I, Type II and Type III – cell mediated – Type IV –
Immunohaematology. Tumor immunology
Max Hours.60

TEXT / REFERENCE BOOKS:

1. Zeev Pancer and Max D. Cooper, (2006), The Evolution of Adaptive Immunity, Ann. Rev. Immunol., 24: 497–518
2. Roitt Evan, Brostoff J. Male D. (1993) Immunology 6th Ed., Mosby & Co. London.
3. Roitt I. M. (1988) Essentials of Immunology, ELBS, London.
4. Roitt M. (1984) Essentials of Immunology, P. G. Publishers Pvt. Ltd., New Delhi.
5. Stites D. P., Stobo J. D., Fudenberg H. H. and Wells J. V., (1982), Basic and Clinical Immunology, 4th Ed.,
Lange Medical Publications, Maruzen Asia Pvt. Ltd., Singapore
6. Janeway Charles A., Paul Travers, Mark Walport, Mark Shlomchik. Immunobiology interactive. 2005. Garland
Science Publishing. USA.

END SEMESTER EXAMINATION QUESTION PAPER PATTERN

Max. Marks: 100 Exam Duration: 3 Hrs.
PART A: 10 questions of 2 marks each - No choice 20 Marks
PART B: 2 questions from each unit of internal choice; each carrying 16 marks 80 Marks
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