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Default Re: Question Paper of GATE Life Sciences

As you require the Question Paper of GATE Life Sciences, so here I am sharing the same with you

One of the parts (A, B, C, D) in the sentence given below contains an ERROR. Which one of the following is INCORRECT?
I requested that he should be given the driving test today instead of tomorrow.
(A) requested that
(B) should be given
(C) the driving test
(D) instead of tomorrow

Which one of the following options is the closest in meaning to the word given below? Latitude
(A) Eligibility (B) Freedom (C) Coercion (D) Meticulousness

Choose the most appropriate word from the options given below to complete the following sentence:

Given the seriousness of the situation that he had to face, his ___ was impressive.
(A) beggary (B) nomenclature (C) jealousy (D) nonchalance

Choose the most appropriate alternative from the options given below to complete the following
sentence: If the tired soldier wanted to lie down, he ___ the mattress out on the balcony.
(A) should take
(B) shall take
(C) should have taken
(D) will have taken

One of the legacies of the Roman legions was discipline. In the legions, military law prevailed and discipline was brutal. Discipline on the battlefield kept units obedient, intact and fighting, even when the odds and conditions were against them.
Which one of the following statements best sums up the meaning of the above passage?
(A) Thorough regimentation was the main reason for the efficiency of the Roman legions even in adverse circumstances.
(B) The legions were treated inhumanly as if the men were animals.
(C) Discipline was the armies’ inheritance from their seniors.
(D) The harsh discipline to which the legions were subjected to led to the odds and conditions being against them.

General Aptitude (GA) Questions (Compulsory)
Q. 1 – Q. 5 carry one mark each.
Q.1 If (1.001)1259 = 3.52 and (1.001)2062 = 7.85, then (1.001)3321 =
(A) 2.23 (B) 4.33 (C) 11.37 (D) 27.64
Q.2 One of the parts (A, B, C, D) in the sentence given below contains an ERROR. Which one of the
following is INCORRECT?
I requested that he should be given the driving test today instead of tomorrow.
(A) requested that
(B) should be given
(C) the driving test
(D) instead of tomorrow
Q.3 Which one of the following options is the closest in meaning to the word given below?
Latitude
(A) Eligibility (B) Freedom (C) Coercion (D) Meticulousness
Q.4 Choose the most appropriate word from the options given below to complete the following
sentence:
Given the seriousness of the situation that he had to face, his ___ was impressive.
(A) beggary (B) nomenclature (C) jealousy (D) nonchalance
Q.5 Choose the most appropriate alternative from the options given below to complete the following
sentence:
If the tired soldier wanted to lie down, he ___ the mattress out on the balcony.
(A) should take
(B) shall take
(C) should have taken
(D) will have taken
Q. 6 - Q. 10 carry two marks each.
Q.6 One of the legacies of the Roman legions was discipline. In the legions, military law prevailed
and discipline was brutal. Discipline on the battlefield kept units obedient, intact and fighting,
even when the odds and conditions were against them.
Which one of the following statements best sums up the meaning of the above passage?
(A) Thorough regimentation was the main reason for the efficiency of the Roman legions even in
adverse circumstances.
(B) The legions were treated inhumanly as if the men were animals.
(C) Discipline was the armies’ inheritance from their seniors.
(D) The harsh discipline to which the legions were subjected to led to the odds and conditions being
against them.
Q.7 A and B are friends. They decide to meet between 1 PM and 2 PM on a given day. There is a
condition that whoever arrives first will not wait for the other for more than 15 minutes. The
probability that they will meet on that day is
(A) 1/4 (B) 1/16 (C) 7/16 (D) 9/16
Q.8 The data given in the following table summarizes the monthly budget of an average household.
Category Amount (Rs.)
Food 4000
Clothing 1200
Rent 2000
Savings 1500
Other expenses 1800
The approximate percentage of the monthly budget NOT spent on savings is
(A) 10% (B) 14% (C) 81% (D) 86%
Q.9 There are eight bags of rice looking alike, seven of which have equal weight and one is slightly
heavier. The weighing balance is of unlimited capacity. Using this balance, the minimum number
of weighings required to identify the heavier bag is
(A) 2 (B) 3 (C) 4 (D) 8
Q.10 Raju has 14 currency notes in his pocket consisting of only Rs. 20 notes and Rs. 10 notes. The total
money value of the notes is Rs. 230. The number of Rs. 10 notes that Raju has is
(A) 5 (B) 6 (C) 9 (D) 10
H : CHEMISTRY (Compulsory)
Q. 1 – Q. 5 carry one mark each.
Q.1 Among the following, the most reactive diene in the Diels-Alder reaction is
(A)
(B)
(C)
(D)
Q.2 The molecule that does NOT absorb the microwave radiation is
(A) CO2 (B) H2O
(C) CO (D) NO
Q.3 The hybridization of atomic orbitals of sulphur in SF4 is
(A) dsp2 (B) sp3d2
(C) sp3d (D) sp3
Q. 6 - Q. 15 carry two marks each.
Q.6 As predicted by MO theory, the bond order and magnetic nature of NO
+
are
(A) three and paramagnetic (B) two and diamagnetic
(C) two and paramagnetic (D) three and diamagnetic
Q.7 The value of ionic product of water changes with temperature. It is 1 10
–14
at 25 oC and 1 10
–13
at 60 C. The CORRECT statement with respect to H and S is
(A) H is negative and S is negative (B) H is positive and S is zero
(C) H is positive and S is negative (D) H is negative and S is positive
Q.8 10 micrograms of the enzyme carbonic anhydrase (molecular weight = 30,000 g/mole) removes
300 milligrams of carbon dioxide per minute from the cells. The turnover number of the enzyme is
(A) 20 min–1 (B) 2 107 min–1
(C) 2 1010 min–1 (D) 7.2 1010 min–1
Q.9 The iodide which reacts most slowly with cyanide ion as a nucleophile in a SN
2 reaction is
(A)
CH3CH2CH2CH2I
(B)
(C)
(D)
(CH3)2CH-I
Q.10 The value of Ka of acetic acid is 1.7 10–5 mol/dm3. The pH of a buffer solution prepared by
mixing 100 ml of 0.1 M acetic acid with a solution of 100 ml of 0.2 M sodium acetate is
(A) 4.1 (B) 4.5
(C) 5.1 (D) 5.5
Q.11 The value of standard half cell potential of Cu+2, Cu couple (E0
Cu(+2), Cu) is 0.34 V. A wire of pure
copper is immersed into a solution of copper nitrate. If the measured cell potential against standard
hydrogen electrode at 298 K is 0.24 V, the molar concentration of copper nitrate is
{Assume activity of Cu+2 = [Cu+2]}.
(A) 4.1 10–4 M (B) 2.0 10–2 M
(C) 3.4 10–2 M (D) 1.8 10–1 M
CH2I
Common Data Questions
Common Data for Questions 12 and 13:
[FeCl4]2– (I), [CoCl4]2– (II) and [NiCl4]2– (III) are paramagnetic tetrahedral complexes.
Q.12 The order of values of crystal field stabilization energy is
(A) I > III > II (B) III > I > II
(C) I > II > III (D) II > III > I
Q.13 The order of values of spin only magnetic moment is
(A) III > II > I (B) III > I > II
(C) II > I > III (D) I > II > III
Linked Answer Questions
Statement for Linked Answer Questions 14 and 15:
Bromine water is decolourised upon reaction with (E)-3-hexene.
Q.14 It is due to
(A) electrophilic addition of bromine to C=C (B) nucleophilic addition of bromine to C=C
(C) electrophilic allylic bromination (D) nucleophilic allylic bromination
I : BIOCHEMISTRY
Q. 1 – Q. 10 carry one mark each.
Q.1 Four proteins (P1, P2, P3 and P4) have 17, 10, 21 and 14 percent hydrophobic amino-acids
respectively. The order of precipitation of these proteins using ammonium sulphate will be
(A) P3, P1, P4, P2 (B) P3, P1, P2, P4 (C) P2, P4, P3, P1 (D) P2, P4, P1, P3
Q.2 Which one of the following pairs of amino-acids in the protein has high propensity to take up the
α-helix conformation?
(A) Gly-Asp (B) Pro-His (C) Gly-Pro (D) Ala-Arg
Q.3 Which one of the following closely defines ‘Molten Globule’ state of a protein?
(A) State with high degree of secondary structure and loss of tertiary structure
(B) State with complete loss of secondary structure
(C) Completely unfolded state
(D) Loss of quaternary structure
Q.4 Which one of the following amino-acids has highest fluorescence quantum yield () in aqueous
solution?
(A) Tyrosine (B) Tryptophan (C) Phenylalanine (D) Histidine
Q.5 Which one of the following compounds does NOT block electron transport?
(A) Cyanide (B) Rotenone (C) Oligomycin (D) Antimycin A
Q.6 The pair of amino-acids which does NOT undergo post-translational modification is
(A) Asn-His (B) Tyr-Ser (C) Asn-Ser (D) Ala-Gly
Q.7 Match the hormones in Group I with their metabolic precursor in Group II
Group I Group II
P. 17-estradiol 1. Arachidonic acid
Q. Thromboxane A2 2. Tyrosine
R. Epinephrine 3. -carotene
S. Retinoic acid 4. Cholesterol
(A) P-4, Q-2, R-3, S-1 (B) P-1, Q-3, R-2, S-4
(C) P-4, Q-1, R-2, S-3 (D) P-1, Q-2, R-4, S-3
Q.8 Upon stimulation of a eukaryotic cell, the intracellular calcium (Ca2+) is released from
(A) Endoplasmic reticulum (B) Nucleus
(C) Peroxisome (D) Mitochondria
Q.9 Leguminous plants maintain a very low concentration of free oxygen in their root nodules because
(A) the nitrogen fixing bacteria living in the root nodules are anaerobic
(B) of binding of oxygen to leghemoglobin
(C) reductase enzyme of the nitrogenase complex helps in removal of O2
(D) nitrogenase enzyme of the nitrogenase complex helps in removal of O2
Q.10 The membrane of mature B cells have
(A) both IgG and IgM (B) both IgG and IgD
(C) both IgM and IgE (D) both IgM and IgD
Q. 11 - Q. 20 carry two marks each.
Q.11 An amino-acid has one proton donating group in the side chain (R). The pKCOOH, pKNH2 and pKR
values for this amino-acid are 2.19, 9.67 and 4.25, respectively. Which one of the following
statements about this amino-acid is CORRECT?
(A) Majority of the molecules will have a net charge of -1 at pH of 7.0
(B) Majority of the molecules will have a net charge of 0 at pH of 4.25
(C) All the molecules will have a deprotonated R group at pH of 3.22
(D) During titration with a strong base, deprotonation will start with the R group
Q.12 Which one of the following bacterial toxins does NOT have ADP-ribosyl transferase activity?
(A) Pertussis toxin (B) Diphtheria toxin
(C) Pseudomonas Exotoxin A (D) S. aureus α-toxin
Q.13 The CORRECT pair of amino-acid sequence and the corresponding target organelle is
(A) KDEL - Golgi (B) K-K/R-X-K/R - Lysosome
(C) SKL - Peroxisome (D) NPVY - Endoplasmic reticulum
Q.14 -oxidation of a 16 carbon fatty acid and a 17 carbon fatty acid leads to formation of
(A) (8 Acetyl CoA) and (8 Acetyl CoA + CO2), respectively
(B) (5 Propionyl CoA + 1 CO2) and (5 Propionyl CoA +1 Acetyl CoA), respectively
(C) (5 Propionyl CoA + 1 CO2) and (5 Propionyl CoA + 2 CO2), respectively
(D) (8 Acetyl CoA) and (7 Acetyl CoA + 1 Propionyl CoA), respectively
Q.15 Pick the correctly matched pairs.
P. Immature B cells — Terminal deoxynucleotidyl transferase
Q. Activated B cells — Class switching
R. Pre B cells — Surrogate light chain
S. Mature B cells — Recombination activating gene 1
(A) P and R (B) Q and R
(C) Q and S (D) Q and P
Q.16 The actual free energy change of a given biochemical reaction carried out under standard
conditions with 1 M initial concentration of each of the reactants and products will be
(A) equal to zero
(B) equal to standard free energy change for the reaction
(C) less than the standard free energy change for the reaction
(D) greater than the standard free energy change for the reaction
Q.17 Match the enzymes in Group I with their corresponding activity in Group II
Group I Group II
P. Flippase 1. Catalyzes the movement of any phospholipid across the lipid bilayer
down its concentration gradient
Q. Floppase 2. Catalyzes the translocation of amino-phospholipids from the
extracellular to the inner leaflet
R. Lipase 3. Catalyzes the translocation of membrane phospholipids from cytosolic to
the extracellular leaflet
S. Scramblase 4. Degradation of phospholipids from the lipid bilayer including the inner
and outer leaflets
(A) P-2, Q-3, R-4, S-1 (B) P-1, Q-2, R-3, S-4
(C) P-4, Q-1, R-2, S-3 (D) P-3, Q-2, R-4, S-1
Q.18 Match the antibiotics in Group I with their mechanism of action in Group II
Group I Group II
P. Tetracyclines 1. Inhibits bacterial protein synthesis by blocking peptidyl transfer
Q. Chloramphenicol 2. Inhibits bacterial protein synthesis by blocking the A-site on the
ribosome
R. Cycloheximide 3. Misreads the genetic code and inhibits initiation of protein
synthesis
S. Streptomycin 4. Inhibits protein synthesis by blocking peptidyl transferase on
80S ribosome
(A) P-2, Q-1, R-3, S-4 (B) P-2, Q-1, R-4, S-3
(C) P-4, Q-3, R-1, S-2 (D) P-3, Q-4, R-2, S-1
Q.19 The kinetics of an enzyme in the presence (+I) or absence (-I) of a reversible inhibitor is described
in the following graph.
If concentration of the reversible inhibitor in +I experiment was equal to 3.0 × 10–3 M, then the
dissociation constant for the enzyme-inhibitor complex is
(A) 1 × 10–3 M (B) 2 × 10–3 M (C) 3 × 10–3 M (D) 4 × 10–3 M

Rest of the Questions are attached in below file which is free of cost
Attached Files Available for Download
File Type: pdf GATE Life Sciences Question Paper 1.pdf (292.0 KB, 15 views)
File Type: pdf GATE Life Sciences Question Paper 2.pdf (272.9 KB, 29 views)
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